The aim of the present literature review work was to develop a bilayer floating bioadhesive drug delivery that the immediate release layer system quickly releases drugs and attains onset of action, subsequently floating bioadhesive sustained release layer floats over gastric fluid and releases the drug in sustained or controlled manner. In bilayer tablet formulation, the floating bioadhesive sustained release layer is compressed and immediate release layer is added over it, then both layers are compressed. Tablets are characterized using the official methods. All the above formulations can evaluated for in vitro drug release, buoyancy lag time (BLT), swelling ability, floating behaviour, adhesion retention period, mucoadhesion study.
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